{"id":114877,"date":"2022-04-12T21:47:23","date_gmt":"2022-04-12T21:47:23","guid":{"rendered":"https:\/\/stg.stg.harmonyadjuvantmelanomastudy.com\/caste-otazky\/"},"modified":"2023-09-21T16:53:08","modified_gmt":"2023-09-21T16:53:08","slug":"caste-otazky","status":"publish","type":"page","link":"https:\/\/stg.harmonyadjuvantmelanomastudy.com\/cs\/caste-otazky\/","title":{"rendered":"\u010cAST\u00c9 OT\u00c1ZKY"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row row_height_percent=&#8220;90&#8243; override_padding=&#8220;yes&#8220; h_padding=&#8220;2&#8243; top_padding=&#8220;5&#8243; bottom_padding=&#8220;5&#8243; back_color=&#8220;color-105898&#8243; back_image=&#8220;110855&#8243; back_position=&#8220;center top&#8220; overlay_alpha=&#8220;50&#8243; gutter_size=&#8220;4&#8243; column_width_percent=&#8220;100&#8243; shift_y=&#8220;0&#8243; z_index=&#8220;0&#8243; top_divider=&#8220;gradient&#8220; bottom_divider=&#8220;step_3_4&#8243; uncode_shortcode_id=&#8220;171042&#8243; 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mobile_width=&#8220;0&#8243; width=&#8220;7\/12&#8243; uncode_shortcode_id=&#8220;128842&#8243;][vc_custom_heading heading_semantic=&#8220;h1&#8243; text_font=&#8220;font-592420&#8243; text_size=&#8220;fontsize-338686&#8243; text_weight=&#8220;700&#8243; text_height=&#8220;fontheight-179065&#8243; text_space=&#8220;fontspace-781688&#8243; uncode_shortcode_id=&#8220;508780&#8243;]\u010cast\u00e9 ot\u00e1zky[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8220;h3&#8243; text_size=&#8220;h3&#8243; text_weight=&#8220;400&#8243; text_height=&#8220;fontheight-357766&#8243; uncode_shortcode_id=&#8220;865545&#8243;]Ot\u00e1zky t\u00fdkaj\u00edc\u00ed se hodnocen\u00e9 l\u00e9\u010dby[\/vc_custom_heading][vc_empty_space empty_h=&#8220;1&#8243;][\/vc_column_inner][vc_column_inner column_width_percent=&#8220;100&#8243; position_vertical=&#8220;middle&#8220; gutter_size=&#8220;3&#8243; style=&#8220;dark&#8220; overlay_alpha=&#8220;50&#8243; shift_x=&#8220;0&#8243; shift_y=&#8220;0&#8243; shift_y_down=&#8220;0&#8243; z_index=&#8220;0&#8243; medium_width=&#8220;4&#8243; mobile_width=&#8220;0&#8243; width=&#8220;5\/12&#8243; uncode_shortcode_id=&#8220;872545&#8243;][vc_single_image media=&#8220;110851&#8243; media_width_percent=&#8220;100&#8243; alignment=&#8220;center&#8220; uncode_shortcode_id=&#8220;192190&#8243;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row row_height_percent=&#8220;0&#8243; override_padding=&#8220;yes&#8220; h_padding=&#8220;2&#8243; top_padding=&#8220;4&#8243; bottom_padding=&#8220;4&#8243; overlay_alpha=&#8220;100&#8243; gutter_size=&#8220;100&#8243; column_width_percent=&#8220;100&#8243; shift_y=&#8220;0&#8243; z_index=&#8220;0&#8243; style=&#8220;inherited&#8220;][vc_column column_width_percent=&#8220;100&#8243; gutter_size=&#8220;3&#8243; overlay_alpha=&#8220;50&#8243; shift_x=&#8220;0&#8243; shift_y=&#8220;0&#8243; shift_y_down=&#8220;0&#8243; z_index=&#8220;0&#8243; medium_width=&#8220;0&#8243; mobile_width=&#8220;0&#8243; zoom_width=&#8220;0&#8243; zoom_height=&#8220;0&#8243; width=&#8220;1\/1&#8243; uncode_shortcode_id=&#8220;790384&#8243;][vc_custom_heading heading_semantic=&#8220;h3&#8243; text_size=&#8220;h3&#8243; text_space=&#8220;fontspace-781688&#8243; uncode_shortcode_id=&#8220;352457&#8243;]Ot\u00e1zky t\u00fdkaj\u00edc\u00ed se hodnocen\u00e9 l\u00e9\u010dby[\/vc_custom_heading][vc_accordion typography=&#8220;yes&#8220; sign=&#8220;plus&#8220; active_tab=&#8220;0&#8243;][vc_accordion_tab gutter_size=&#8220;2&#8243; column_padding=&#8220;2&#8243; title=&#8220;Jak\u00e9 hodnocen\u00e9 l\u00e9\u010dby se mi dostane v pr\u016fb\u011bhu studie?&#8220; tab_id=&#8220;24a731b5-e185-3&#8243;][vc_column_text uncode_shortcode_id=&#8220;165891&#8243;]Budete n\u00e1hodn\u011b za\u0159azen\/a do l\u00e9\u010debn\u00e9 skupiny, ve kter\u00e9 budete dost\u00e1vat dva hodnocen\u00e9 p\u0159\u00edpravky (skupina s n\u00edzkou d\u00e1vkou nebo skupina s vysokou d\u00e1vkou) nebo mo\u017enost l\u00e9\u010dby b\u011b\u017en\u011b pou\u017e\u00edvanou k prevenci n\u00e1vratu melanomu po operaci odstran\u011bn\u00ed rakoviny zvan\u00e9 pembrolizumab, s placebem.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8220;2&#8243; column_padding=&#8220;2&#8243; title=&#8220;Co znamen\u00e1 hodnocen\u00fd p\u0159\u00edpravek?&#8220; tab_id=&#8220;1666717276638-7-7&#8243;][vc_column_text uncode_shortcode_id=&#8220;115688&#8243;]Hodnocen\u00fd p\u0159\u00edpravek znamen\u00e1, \u017ee bezpe\u010dnost a \u00fa\u010dinnost hodnocen\u00fdch p\u0159\u00edpravk\u016f nebyly pln\u011b vyhodnoceny a v sou\u010dasn\u00e9 dob\u011b nejsou schv\u00e1leny regula\u010dn\u00edmi zdravotn\u00edmi \u00fa\u0159ady pro danou zemi k pou\u017eit\u00ed p\u0159i l\u00e9\u010db\u011b konkr\u00e9tn\u00edho onemocn\u011bn\u00ed, ale mohou b\u00fdt pou\u017eity pro \u00fa\u010dely klinick\u00e9ho v\u00fdzkumu.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8220;2&#8243; column_padding=&#8220;2&#8243; title=&#8220;Jak hodnocen\u00e9 p\u0159\u00edpravky funguj\u00ed?&#8220; tab_id=&#8220;51669b3a-8e8e-2&#8243;][vc_column_text uncode_shortcode_id=&#8220;204986&#8243;]Hodnocen\u00e9 p\u0159\u00edpravky funguj\u00ed tak, \u017ee pom\u00e1haj\u00ed imunitn\u00edm bu\u0148k\u00e1m naj\u00edt a zni\u010dit n\u00e1dorov\u00e9 bu\u0148ky.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8220;2&#8243; column_padding=&#8220;2&#8243; title=&#8220;Jsou n\u011bkter\u00fd ze hodnocen\u00fdch p\u0159\u00edpravk\u016f ji\u017e pou\u017e\u00edv\u00e1ny k l\u00e9\u010db\u011b pokro\u010dil\u00e9ho melanomu?&#8220; tab_id=&#8220;ef5915c9-1af0-2&#8243;][vc_column_text uncode_shortcode_id=&#8220;152079&#8243;]Pembrolizumab je v n\u011bkter\u00fdch zem\u00edch schv\u00e1len jako mo\u017enost l\u00e9\u010dby melanomu u dosp\u011bl\u00fdch. Jeden z dal\u0161\u00edch hodnocen\u00fdch p\u0159\u00edpravk\u016f je schv\u00e1len v n\u011bkter\u00fdch zem\u00edch jako mo\u017enost l\u00e9\u010dby jin\u00fdch typ\u016f rakoviny, ale v sou\u010dasn\u00e9 dob\u011b nen\u00ed schv\u00e1len pro l\u00e9\u010dbu melanomu. T\u0159et\u00ed hodnocen\u00fd p\u0159\u00edpravek nen\u00ed v \u017e\u00e1dn\u00e9 zemi schv\u00e1len pro \u017e\u00e1dn\u00fd druh l\u00e9\u010dby.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8220;2&#8243; column_padding=&#8220;2&#8243; title=&#8220;Co je to placebo?&#8220; tab_id=&#8220;0a882431-6c4b-0&#8243;][vc_column_text uncode_shortcode_id=&#8220;188105&#8243;]Placebo vypad\u00e1 jako hodnocen\u00fd l\u00e9k, ale ve skute\u010dnosti se jedn\u00e1 o napodobeninu l\u00e9\u010div\u00e9ho p\u0159\u00edpravku, kter\u00e1 neobsahuje \u017e\u00e1dnou aktivn\u00ed l\u00e1tku. V\u00fdzkumn\u00ed pracovn\u00edci tak maj\u00ed co porovn\u00e1vat s hodnocen\u00fdmi l\u00e9ky s c\u00edlem pochopit jejich \u00fa\u010dinky. Nikdo ve studii nebude dost\u00e1vat pouze placebo. Ka\u017ed\u00fd bude dost\u00e1vat aktivn\u00ed protin\u00e1dorovou l\u00e9\u010dbu. Ka\u017ed\u00fd bude dost\u00e1vat aktivn\u00ed protin\u00e1dorovou l\u00e9\u010dbu.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8220;2&#8243; column_padding=&#8220;2&#8243; title=&#8220;Jak jsou p\u0159i\u0159azeny skupiny hodnocen\u00e9 l\u00e9\u010dby?&#8220; tab_id=&#8220;1659029436671-5-0&#8243;][vc_column_text uncode_shortcode_id=&#8220;211551&#8243;]K n\u00e1hodn\u00e9mu rozd\u011blen\u00ed \u00fa\u010dastn\u00edk\u016f do l\u00e9\u010debn\u00fdch skupin se pou\u017e\u00edv\u00e1 po\u010d\u00edta\u010d, podobn\u011b jako kdy\u017e se rozd\u00e1v\u00e1 z nam\u00edchan\u00e9ho bal\u00ed\u010dku karet. To se naz\u00fdv\u00e1 randomizace.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8220;2&#8243; column_padding=&#8220;2&#8243; title=&#8220;Existuj\u00ed n\u011bjak\u00e9 vedlej\u0161\u00ed \u00fa\u010dinky hodnocen\u00fdch p\u0159\u00edpravk\u016f?&#8220; tab_id=&#8220;1659029463838-6-5&#8243;][vc_column_text uncode_shortcode_id=&#8220;143517&#8243;]Jako u v\u0161ech l\u00e9k\u016f existuje mo\u017enost, \u017ee se vyskytnou vedlej\u0161\u00ed \u00fa\u010dinky, co\u017e jsou necht\u011bn\u00e9 a nezam\u00fd\u0161len\u00e9 \u00fa\u010dinky dan\u00e9ho l\u00e9ku. Dal\u0161\u00ed informace o mo\u017en\u00fdch ne\u017e\u00e1douc\u00edch \u00fa\u010dinc\u00edch z\u00edsk\u00e1te od zkou\u0161ej\u00edc\u00edho l\u00e9ka\u0159e. V\u00e1\u0161 zdravotn\u00ed stav bude po celou dobu studie pe\u010dliv\u011b sledov\u00e1n. Je velmi d\u016fle\u017eit\u00e9 informovat zkou\u0161ej\u00edc\u00edho l\u00e9ka\u0159e, pokud si v\u0161imnete jak\u00fdchkoli zm\u011bn sv\u00e9ho zdravotn\u00edho stavu nebo pokud V\u00e1s n\u011bco obt\u011b\u017euje.[\/vc_column_text][\/vc_accordion_tab][\/vc_accordion][vc_empty_space empty_h=&#8220;3&#8243;][vc_custom_heading heading_semantic=&#8220;h3&#8243; text_size=&#8220;h3&#8243; text_space=&#8220;fontspace-781688&#8243; uncode_shortcode_id=&#8220;859334&#8243;]Obecn\u00e9 ot\u00e1zky ke studii[\/vc_custom_heading][vc_accordion typography=&#8220;yes&#8220; sign=&#8220;plus&#8220; active_tab=&#8220;0&#8243;][vc_accordion_tab gutter_size=&#8220;2&#8243; column_padding=&#8220;2&#8243; title=&#8220;Jak dlouho budu ve studii?&#8220; tab_id=&#8220;1666716724-1-95&#8243;][vc_column_text uncode_shortcode_id=&#8220;378920&#8243;]Ve studii m\u016f\u017eete b\u00fdt a\u017e 5 let.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8220;2&#8243; column_padding=&#8220;2&#8243; title=&#8220;Kolikr\u00e1t se budu muset dostavit na studijn\u00ed pracovi\u0161t\u011b?&#8220; tab_id=&#8220;1666716724-2-33&#8243;][vc_column_text uncode_shortcode_id=&#8220;172396&#8243;]N\u00e1v\u0161t\u011bvy v r\u00e1mci studie budou prob\u00edhat p\u0159ibli\u017en\u011b ka\u017ed\u00e9 3 t\u00fddny po dobu 12 m\u011bs\u00edc\u016f. Budete zde dost\u00e1vat hodnocenou l\u00e9\u010dbu a absolvovat testy, kter\u00e9 pomohou zajistit bezpe\u010dn\u00e9 pokra\u010dov\u00e1n\u00ed l\u00e9\u010dby. P\u0159ibli\u017en\u011b ka\u017ed\u00fdch 12 t\u00fddn\u016f budete tak\u00e9 absolvovat kontroln\u00ed vy\u0161et\u0159en\u00ed. Po pod\u00e1n\u00ed posledn\u00ed d\u00e1vky hodnocen\u00e9 l\u00e9\u010dby bude frekvence va\u0161ich n\u00e1v\u0161t\u011bv na v\u00fdzkumn\u00e9m pracovi\u0161ti z\u00e1viset na stavu va\u0161eho n\u00e1doru.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8220;2&#8243; column_padding=&#8220;2&#8243; title=&#8220;Jak\u00e9 jsou v\u00fdhody \u00fa\u010dasti v klinick\u00e9 studii?&#8220; tab_id=&#8220;1666716837187-2-3&#8243;][vc_column_text uncode_shortcode_id=&#8220;368788&#8243;]Va\u0161e \u00fa\u010dast v klinick\u00e9 studii v\u00e1m m\u016f\u017ee \u010di nemus\u00ed p\u0159in\u00e9st p\u0159\u00edm\u00fd prosp\u011bch. Budete v\u0161ak pr\u016fb\u011b\u017en\u011b sledov\u00e1ni l\u00e9ka\u0159i s odborn\u00fdmi znalostmi v oblasti melanomu k\u016f\u017ee a ve\u0161ker\u00e9 informace z\u00edskan\u00e9 b\u011bhem studie mohou l\u00e9ka\u0159\u016fm pomoci z\u00edskat v\u00edce informac\u00ed o l\u00e9\u010db\u011b dal\u0161\u00edch pacient\u016f s melanomem.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8220;2&#8243; column_padding=&#8220;2&#8243; title=&#8220;Bude m\u011b \u00fa\u010dast ve studii n\u011bco st\u00e1t?&#8220; tab_id=&#8220;1666716838989-3-9&#8243;][vc_column_text uncode_shortcode_id=&#8220;148623&#8243;]Za hodnocen\u00e9 p\u0159\u00edpravky, n\u00e1v\u0161t\u011bvy, vy\u0161et\u0159en\u00ed nebo spot\u0159ebn\u00ed materi\u00e1l, kter\u00e9 jsou pro studii nezbytn\u00e9, nebudete nic platit.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8220;2&#8243; column_padding=&#8220;2&#8243; title=&#8220;Kdo je zadavatelem studie?&#8220; tab_id=&#8220;1666716840438-4-8&#8243;][vc_column_text uncode_shortcode_id=&#8220;114846&#8243;]Zadavatelem studie HARMONY-Adjuvant je biotechnologick\u00e1 spole\u010dnost Regeneron Pharmaceuticals. Ta plat\u00ed zkou\u0161ej\u00edc\u00edmu l\u00e9ka\u0159i a studijn\u00edmu pracovi\u0161ti za realizaci t\u00e9to studie.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8220;2&#8243; column_padding=&#8220;2&#8243; title=&#8220;Co kdy\u017e se rozhodnu z\u00fa\u010dastnit se studie a pot\u00e9 si to rozmysl\u00edm?&#8220; tab_id=&#8220;1666716966938-5-6&#8243;][vc_column_text uncode_shortcode_id=&#8220;133429&#8243;]\u00da\u010dast ve studii je zcela dobrovoln\u00e1. Pokud se rozhodnete do studie vstoupit a pak si to rozmysl\u00edte, m\u016f\u017eete ji kdykoli opustit.[\/vc_column_text][\/vc_accordion_tab][\/vc_accordion][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row row_height_percent=&#8220;90&#8243; override_padding=&#8220;yes&#8220; h_padding=&#8220;2&#8243; top_padding=&#8220;5&#8243; bottom_padding=&#8220;5&#8243; back_color=&#8220;color-105898&#8243; back_image=&#8220;110855&#8243; back_position=&#8220;center top&#8220; overlay_alpha=&#8220;50&#8243; gutter_size=&#8220;4&#8243; column_width_percent=&#8220;100&#8243; shift_y=&#8220;0&#8243; z_index=&#8220;0&#8243; top_divider=&#8220;gradient&#8220; bottom_divider=&#8220;step_3_4&#8243; uncode_shortcode_id=&#8220;171042&#8243; back_color_type=&#8220;uncode-palette&#8220;][vc_column column_width_percent=&#8220;100&#8243; [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-114877","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - 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