{"id":115992,"date":"2022-04-12T21:47:23","date_gmt":"2022-04-12T21:47:23","guid":{"rendered":"https:\/\/stg.stg.harmonyadjuvantmelanomastudy.com\/faqs\/"},"modified":"2023-06-29T18:19:11","modified_gmt":"2023-06-29T18:19:11","slug":"faqs","status":"publish","type":"page","link":"https:\/\/stg.harmonyadjuvantmelanomastudy.com\/en-uk\/faqs\/","title":{"rendered":"FAQs"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row row_height_percent=&#8221;90&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;5&#8243; bottom_padding=&#8221;5&#8243; back_color=&#8221;color-105898&#8243; back_image=&#8221;110855&#8243; back_position=&#8221;center top&#8221; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; top_divider=&#8221;gradient&#8221; bottom_divider=&#8221;step_3_4&#8243; uncode_shortcode_id=&#8221;171042&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_percent=&#8221;100&#8243; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;6&#8243; style=&#8221;dark&#8221; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;744311&#8243;][vc_row_inner row_inner_height_percent=&#8221;0&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; inverted_device_order=&#8221;yes&#8221; limit_content=&#8221;&#8221;][vc_column_inner column_width_percent=&#8221;100&#8243; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;2&#8243; style=&#8221;dark&#8221; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;4&#8243; align_mobile=&#8221;align_center_mobile&#8221; mobile_width=&#8221;0&#8243; width=&#8221;7\/12&#8243; uncode_shortcode_id=&#8221;128842&#8243;][vc_custom_heading heading_semantic=&#8221;h1&#8243; text_font=&#8221;font-146862&#8243; text_size=&#8221;fontsize-338686&#8243; text_weight=&#8221;400&#8243; text_height=&#8221;fontheight-179065&#8243; text_space=&#8221;fontspace-781688&#8243; uncode_shortcode_id=&#8221;302619&#8243;]Frequently Asked Questions[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;h3&#8243; text_weight=&#8221;400&#8243; text_height=&#8221;fontheight-357766&#8243; uncode_shortcode_id=&#8221;865545&#8243;]Study Treatment Questions[\/vc_custom_heading][vc_empty_space empty_h=&#8221;1&#8243;][\/vc_column_inner][vc_column_inner column_width_percent=&#8221;100&#8243; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; style=&#8221;dark&#8221; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;4&#8243; mobile_width=&#8221;0&#8243; width=&#8221;5\/12&#8243; uncode_shortcode_id=&#8221;872545&#8243;][vc_single_image media=&#8221;110851&#8243; media_width_percent=&#8221;100&#8243; alignment=&#8221;center&#8221; uncode_shortcode_id=&#8221;192190&#8243;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;4&#8243; bottom_padding=&#8221;4&#8243; overlay_alpha=&#8221;100&#8243; gutter_size=&#8221;100&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; style=&#8221;inherited&#8221;][vc_column column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; zoom_width=&#8221;0&#8243; zoom_height=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;790384&#8243;][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;h3&#8243; text_space=&#8221;fontspace-781688&#8243; uncode_shortcode_id=&#8221;352457&#8243;]Study Treatment Questions[\/vc_custom_heading][vc_accordion typography=&#8221;yes&#8221; sign=&#8221;plus&#8221; active_tab=&#8221;0&#8243;][vc_accordion_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;What study treatment will I receive during the study?&#8221; tab_id=&#8221;24a731b5-e185-3&#8243;][vc_column_text uncode_shortcode_id=&#8221;165891&#8243;]You will be placed by chance into a treatment group to receive the two study drugs (low dose group or high dose group) or a treatment option commonly used to prevent melanoma from returning after cancer removal surgery called pembrolizumab, with a placebo.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;What does study drug mean?&#8221; tab_id=&#8221;1666717276638-7-7&#8243;][vc_column_text uncode_shortcode_id=&#8221;115688&#8243;]Study drug means that the safety and effectiveness of the study drugs have not been fully evaluated and are not currently approved by country-specific regulatory health authorities to be used to treat a specific disease, but is allowed to be used for clinical research purposes.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;How do the study drugs work?&#8221; tab_id=&#8221;51669b3a-8e8e-2&#8243;][vc_column_text uncode_shortcode_id=&#8221;204986&#8243;]The study drugs work by helping your immune cells find and destroy cancer cells.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;Are any of the study drugs already used to treat advanced melanoma?&#8221; tab_id=&#8221;ef5915c9-1af0-2&#8243;][vc_column_text uncode_shortcode_id=&#8221;152079&#8243;]Pembrolizumab is approved in some countries as a treatment option for melanoma in adults. One of the other study drugs is approved in some countries as a treatment option in other types of cancer, but currently not approved for melanoma. The third study drug is not approved in any country for any kind of treatment.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;What is a placebo?&#8221; tab_id=&#8221;0a882431-6c4b-0&#8243;][vc_column_text uncode_shortcode_id=&#8221;188105&#8243;]A placebo looks like the study drug but has no active medicine in it. This gives researchers something to compare the study drug to in order to better understand its effects. No one in the study will receive placebo only. Everyone will receive an active anti-cancer treatment.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;How are the study treatment groups assigned?&#8221; tab_id=&#8221;1659029436671-5-0&#8243;][vc_column_text uncode_shortcode_id=&#8221;211551&#8243;]A computer is used to assign participants to study treatment groups by chance, like dealing from a shuffled deck of cards. This is called randomization.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;Are there any side effects from the study drugs?&#8221; tab_id=&#8221;1659029463838-6-5&#8243;][vc_column_text uncode_shortcode_id=&#8221;143517&#8243;]Like with all medicines, there is a chance for side effects, which are unwanted and unintended effects from a medicine. Talk to the study doctor for more information on possible side effects. Your health will be closely monitored during the entire study. It is very important to tell the study doctor if you notice any changes in your health or if anything is bothering you.[\/vc_column_text][\/vc_accordion_tab][\/vc_accordion][vc_empty_space empty_h=&#8221;3&#8243;][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;h3&#8243; text_space=&#8221;fontspace-781688&#8243; uncode_shortcode_id=&#8221;859334&#8243;]General Study Questions[\/vc_custom_heading][vc_accordion typography=&#8221;yes&#8221; sign=&#8221;plus&#8221; active_tab=&#8221;0&#8243;][vc_accordion_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;How long will I be in the study?&#8221; tab_id=&#8221;1666716724-1-95&#8243;][vc_column_text uncode_shortcode_id=&#8221;378920&#8243;]You may be in the study for up to 5 years.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;How many times will I have to go to the study site?&#8221; tab_id=&#8221;1666716724-2-33&#8243;][vc_column_text uncode_shortcode_id=&#8221;172396&#8243;]You will have study visits approximately every 3 weeks for 12 months to receive study treatment and have tests to help ensure that the treatment can be continued safely. You will also have surveillance scans approximately every 12 weeks. After your last dose of study treatment, how often you come to the study site will depend on your tumor status.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;What are the benefits of being in the clinical study?&#8221; tab_id=&#8221;1666716837187-2-3&#8243;][vc_column_text uncode_shortcode_id=&#8221;368788&#8243;]You may or may not directly benefit from being in the clinical study. However, you will have continuous monitoring from doctors with expertise in melanoma skin cancer, and any information collected during the study may help doctors learn more about treating others with melanoma.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;Will it cost me anything to be in the study?&#8221; tab_id=&#8221;1666716838989-3-9&#8243;][vc_column_text uncode_shortcode_id=&#8221;148623&#8243;]There will be no cost to you for the study drugs, visits, tests, or supplies that are required for the study.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;Who is sponsoring the study?&#8221; tab_id=&#8221;1666716840438-4-8&#8243;][vc_column_text uncode_shortcode_id=&#8221;114846&#8243;]The biotechnology company Regeneron Pharmaceuticals is sponsoring the HARMONY-Adjuvant Study. They pay the study doctor and study site to run this study.[\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;What if I decide to join the study and then change my mind?&#8221; tab_id=&#8221;1666716966938-5-6&#8243;][vc_column_text uncode_shortcode_id=&#8221;133429&#8243;]Being in the study is completely voluntary. If you decide to join and then change your mind, you can leave the study at any time.[\/vc_column_text][\/vc_accordion_tab][\/vc_accordion][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row row_height_percent=&#8221;90&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;5&#8243; bottom_padding=&#8221;5&#8243; back_color=&#8221;color-105898&#8243; back_image=&#8221;110855&#8243; back_position=&#8221;center top&#8221; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; top_divider=&#8221;gradient&#8221; bottom_divider=&#8221;step_3_4&#8243; uncode_shortcode_id=&#8221;171042&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_percent=&#8221;100&#8243; [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-115992","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/stg.harmonyadjuvantmelanomastudy.com\/en-uk\/wp-json\/wp\/v2\/pages\/115992","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg.harmonyadjuvantmelanomastudy.com\/en-uk\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/stg.harmonyadjuvantmelanomastudy.com\/en-uk\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/stg.harmonyadjuvantmelanomastudy.com\/en-uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/stg.harmonyadjuvantmelanomastudy.com\/en-uk\/wp-json\/wp\/v2\/comments?post=115992"}],"version-history":[{"count":0,"href":"https:\/\/stg.harmonyadjuvantmelanomastudy.com\/en-uk\/wp-json\/wp\/v2\/pages\/115992\/revisions"}],"wp:attachment":[{"href":"https:\/\/stg.harmonyadjuvantmelanomastudy.com\/en-uk\/wp-json\/wp\/v2\/media?parent=115992"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}